Samuel Denmeade

Dr. Samuel Ray Denmeade is an oncologist at the Johns Hopkins University School of Medicine.

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In addition to being an oncologist, he maintains an active research interest in novel ways to treat prostate cancer. He has been a key researcher in a number of cancer treatments, including engineering the bacterial toxin Aerolysin to target cancer cells. Other research includes the study of proteases, with the theory that a lethal drug could be disguised as a prodrug and only released when exposed to the enzymatic activity of PSA, PSA being present in its enzymatically active form only in the tumor and not elsewhere in the body.