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Rosai-Dorfman disease



Rosai-Dorfman disease, also known as sinus histiocytosis with massive lymphadenopathy, is a rare, benign disorder of unknown etiology that is characterized by the overproduction of histiocytes, which accumulate in lymph nodes throughout the body. Lymphadenopathy of the neck is the most common place of histiocyte accumulation, although accumulation outside of lymph nodes may occur, as well. The most common sites of accumulation outside of the lymph nodes are skin, upper respiratory tract, and bone.[1] The symptoms of this disease vary with the site of accumulation.

References

  1. ^ Foucar E, Rosai J, Dorfman R (1990). "Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease): review of the entity". Semin Diagn Pathol 7 (1): 19–73. PMID 2180012. Retrieved on 2007-11-05.


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Rosai-Dorfman_disease". A list of authors is available in Wikipedia.
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