Proglucagon

Proglucagon is a precursor of glucagon, and several other components. It is generated in the alpha cells of the pancreas, and it consists of the following:

• Glicentin
  • Glicentin-related pancreatic polypeptide (GRPP)
  • Oxyntomodulin
    • Glucagon
    • intervening peptide 1
• major proglucagon fragment (MPGF)
  • GLP-1
  • intervening peptide 2
  • GLP-2

v • d • e Gastrointestinal hormones, pancreatic hormones: proglucagon
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