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Piperonyl butoxide



Piperonyl butoxide
IUPAC name Piperonyl butoxide
Identifiers
CAS number 51-03-6
Properties
Molecular formula C19H30N5
Molar mass 338.43 g/mol
Density 1.05 g/cm3
Boiling point

155 °C

Hazards
Flash point 171 °C
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)
Infobox disclaimer and references

Piperonyl butoxide (PBO) is a pesticide synergist. It does not, by itself have pesticidal properties. However, when added to insecticide mixtures, typically pyrethrin, pyrethroid, and carbamate insecticides, their potency is increased considerably.[1]

Piperonyl butoxide is a potent cytochrome P450 inhibitor. This family of enzymes act as the principal detoxification pathway for many pesticides. Inhibiting the detoxification pathway allows higher unmetabolised systemic concentrations of the active insecticide to remain within the target animal for a longer period.

Piperonyl butoxide is moderately stable, and is a semisynthetic derivative of safrole.

It is debatable whether the substance is oncogenic, mutagenic, or teratogenic in humans. Its acute oral and dermal toxicity in mammals is low, however it is toxic to fish and potentiates rotenone.[2]

References

  1. ^ National Pesticide Information Center - Piperonyl Butoxide General Fact Sheet
  2. ^ National Pesticide Information Center - Piperonyl Butoxide Technical Fact Sheet
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Piperonyl_butoxide". A list of authors is available in Wikipedia.
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