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PentastarchPentastarch is a synthetic derivative of starch, which has five hydroxyethyl groups. It is sold under the name Pentaspan and used for fluid resuscitation. It is considered a plasma expander because it remains primarily intravascular after infusion. Additional recommended knowledge
Choice of resuscitation fluidThe choice of fluid (normal saline vs. Ringer's lactate vs. pentaspan) is controversial.[1] Physiologically, fluid with pentaspan stays primarily in the blood plasma. This is different than normal saline, which shifts quickly into the intracellular compartment. Advocates of pentaspan use believe that:
Normal saline versus pentastarchCasualtyPentastarch in the emergency setting is not well studied and its use not of proven benefit. One small study, comparing normal saline and pentastarch, failed to show any significant survival advantage; however, significantly less volume was required for resuscitation in the pentastarch group.[2] Cardiac surgeryA study is currently being done to compare normal saline with pentastarch following cardiac surgery.[3] CostPentastarch is more expensive than normal saline, but less expensive than albumin. References
See alsoCategories: Medical treatments | Intravenous fluids |
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This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Pentastarch". A list of authors is available in Wikipedia. |