Non-stop decay

Non-stop decay is a recently identified cellular mechanism of mRNA surveillance to detect mRNA molecules lacking a stop codon and prevent these mRNAs from translation. The non-stop decay pathway releases ribosomes that have reach the far 3' end of a mRNA and guides the mRNA to the exosome complex for degradation. ^[1]

See also

• Nonsense mediated decay, another mRNA surveillance mechanism

References

1. ^ Vasudevan et al. (2002). "Non-stop decay--a new mRNA surveillance pathway". Bioessays 24: 785-8. PMID 12210514.