To use all functions of this page, please activate cookies in your browser.
my.bionity.com
With an accout for my.bionity.com you can always see everything at a glance – and you can configure your own website and individual newsletter.
- My watch list
- My saved searches
- My saved topics
- My newsletter
Nelson's syndrome
Nelson's syndrome is the rapid enlargement of a pituitary adenoma that occurs after the removal of both adrenal glands. Additional recommended knowledgeRemoval of both adrenal glands, or bilateral adrenalectomy, is an operation for Cushing's Disease. Removal of both adrenals eliminates production of cortisol, and the lack of cortisol's negative feedback can allow any preexisting pituitary adenoma to grow unchecked. Continued growth can cause mass effects due to physical compression of brain tissue, along with increased production of adrenocorticotrophic hormone (ACTH) and melanocyte stimulating hormone (MSH). The common signs and symptoms include muscle weakness and skin hyperpigmentation due to excess MSH. Nelson's syndrome is rare because bilateral adrenalectomy is now only used in extreme circumstances. References
|
||||||
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Nelson's_syndrome". A list of authors is available in Wikipedia. |