Myoglobinuria

Myoglobinuria is the presence of myoglobin in the urine, usually associated with rhabdomyolysis or muscle destruction. Myoglobin is present in muscle cells as a reserve of oxygen.

Additional recommended knowledge

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Essential Laboratory Skills Guide

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Causes

Trauma, vascular problems, venoms, certain drugs and other situations can destroy or damage the muscle, releasing myoglobin to the circulation and thus to the kidneys.

Under ideal situations myoglobin will be filtered and excreted with the urine, but if too much myoglobin is released into the circulation or in case of renal problems, it can occlude the renal filtration system leading to acute tubular necrosis and acute renal insufficiency.

Useful information

After centrifuge, the serum of myologinuria is clear, where the serum of hemoglobinuria after centrifuge is pink.

Drugs that have been shown to induce myoglobinuria include RISPERDAL. This drug is given to adolescents who show signs of schizophrenia in 1-4mg doses. WARNING: BE Careful, the side effects are many and are written in scientific lingo. Research before your child is put on this drug, diet and parental involvement are the best cure.