My watch list
my.bionity.com  

my.bionity.com

With an accout for my.bionity.com you can always see everything at a glance – and you can configure your own website and individual newsletter.

  • My watch list
  • My saved searches
  • My saved topics
  • My newsletter
Register free of charge
Login  
eng  
DeutschEnglishFrançaisEspañol

Marburg multiple sclerosis



Marburg multiple sclerosis, also known as malignant, acute or fulminant multiple sclerosis, is considered one of the multiple sclerosis borderline diseases, which is a collection of diseases classified by some as MS variants and by others as different diseases. Other diseases in this group are Neuromyelitis optica (NMO), Balo concentric sclerosis and Schilder's disease.[1]

It took its name from Otto Marburg. It can be diagnosed in vivo with an MRI.[2]

It is usually lethal, but recently it has been found to be responsive to Mitoxantrone[3] and Alemtuzumab,[4] and it has also been responsive to autologous stem cells transplantation.[5]

See also

References

  1. ^ Fontaine B (2001). "Borderline forms of multiple sclerosis" (in French). Rev. Neurol. (Paris) 157 (8-9 Pt 2): 929-34. PMID 11787357.
  2. ^ In vivo MRI diagnosis
  3. ^ Responsiveness to Mitoxantrone
  4. ^ Alemtuzumab and craniotomy for severe acute demyelinating illness [1]
  5. ^ Kimiskidis VK, Sakellari I, Tsimourtou V, et al (2007). "Autologous stem-cell transplantation in malignant multiple sclerosis: a case with a favorable long-term outcome". doi:10.1177/1352458507082604. PMID 17942513.


v • d • e
Multiple sclerosis
Signs and symptomsAtaxia · Depression · Diplopia · Dysarthria · Dysphagia · Fatigue · Incontinence · Neurological fatigue · Nystagmus · Optic neuritis · Pain
Diagnosis and evolution followingMcDonald criteria · EDSS
InvestigationPathophysiology · Experimental autoimmune encephalomyelitis
TreatmentInterferon · Glatiramer acetate · Mitoxantrone · Natalizumab · Therapies under investigation
Borderline formsAcute disseminated encephalomyelitis · Balo concentric sclerosis · Devic's disease · Guillain-Barré syndrome · Marburg multiple sclerosis · Schilder's disease
OtherList of people with multiple sclerosis · List of multiple sclerosis organizations


v • d • e
Nervous system pathology, primarily CNS (G00-G47, 320-349)
Inflammatory diseases
of the CNS		Meningitis (Arachnoiditis) - Encephalitis - Myelitis - Encephalomyelitis (Acute disseminated) - Tropical spastic paraparesis
Systemic atrophies
primarily affecting the CNS		Huntington's disease - Spinocerebellar ataxia (Friedreich's ataxia, Ataxia telangiectasia, Hereditary spastic paraplegia)
Spinal muscular atrophy: Werdnig-Hoffman disease - Kugelberg-Welander disease - Fazio Londe syndrome -
MND (Amyotrophic lateral sclerosis (ALS), Progressive muscular atrophy (PMA), Progressive bulbar, Pseudobulbar, PLS)
Extrapyramidal and
movement disorders		Parkinson's disease - Neuroleptic malignant syndrome - Postencephalitic parkinsonism - Pantothenate kinase-associated neurodegeneration - Progressive supranuclear palsy - Striatonigral degeneration - Dystonia (Spasmodic torticollis, Meige's syndrome, Blepharospasm) - Essential tremor - Myoclonus - Chorea (Choreoathetosis) - Restless legs syndrome - Stiff person syndrome
Other degenerative /
demyelinating diseases		Alzheimer's disease - Pick's disease - Alpers' disease - Dementia with Lewy bodies - Leigh's disease - Multiple sclerosis - Devic's disease - Central pontine myelinolysis - Transverse myelitis
Seizure/epilepsyFocal (Simple partial, Complex partial) - Generalised (Tonic-clonic, Absence, Atonic, Benign familial neonatal) - Lennox-Gastaut - West - Epilepsia partialis continua - Status epilepticus (Complex partial status epilepticus)
HeadacheMigraine (Familial hemiplegic) - Cluster - Vascular - Tension
VascularTransient ischemic attack (Amaurosis fugax, Transient global amnesia) - Cerebrovascular disease (MCA, ACA, PCA, Foville's syndrome, Millard-Gubler syndrome, Lateral medullary syndrome, Weber's syndrome, Lacunar stroke)
Sleep disordersInsomnia - Hypersomnia - Sleep apnea (Ondine's curse) - Narcolepsy - Cataplexy - Kleine-Levin syndrome - Circadian rhythm sleep disorder - Delayed sleep phase syndrome - Advanced sleep phase syndrome
OtherHydrocephalus (Normal pressure) - Idiopathic intracranial hypertension - Encephalopathy - Brain herniation - Cerebral edema - Reye's syndrome - Syringomyelia - Syringobulbia - Spinal cord compression
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Marburg_multiple_sclerosis". A list of authors is available in Wikipedia.
Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE