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Macrocephaly

**Macrocephaly**
*Classification & external resources*
ICD-10	Q75.3
ICD-9	756.0
OMIM	248000
DiseasesDB	22519
MedlinePlus	003305

Macrocephaly (from the Greek words μακρύς, meaning "long", and κεφάλη, meaning "head"), is when the head circumference is larger than average for the age and sex of the infant or child.

Additional recommended knowledge

Correct Test Weight Handling Guide: 12 Practical Tips

Essential Laboratory Skills Guide

Daily Sensitivity Test

Causes

It is sometimes associated with certain disorders. Macrocephaly also may be inherited.

Macrocephaly may be caused by an enlarged brain or hydrocephalus. It may be associated with other disorders such as dwarfism, autism, neurofibromatosis, glutaric acidemia type 1 (GA1), tuberous sclerosis and Cowden disease (multiple hamartoma syndrome).

v • d • e Congenital malformations and deformations of musculoskeletal system (Q65-Q79, 754-756)
Limbs	hip: Dislocation of hip/Hip dysplasia feet (Club foot, Flat feet, Pes cavus) head, face, spine and chest: skull, face and jaw (Dolichocephaly, Plagiocephaly) - Scoliosis - chest (Pectus excavatum, Pectus carinatum) Polydactyly/Syndactyly (Webbed toes) reduction deficits (Ectrodactyly, Amelia, Phocomelia) upper limb (Cleidocranial dysostosis, Madelung's deformity, Sprengel's deformity) knee (Genu valgum, Genu varum) Arthrogryposis
Skull and face bones	Craniosynostosis (Scaphocephaly) - Trigonocephaly - Oxycephaly - Crouzon syndrome - Hypertelorism - Macrocephaly - Treacher Collins syndrome - Platybasia
Spine and bony thorax	Klippel-Feil syndrome - Spondylolisthesis - Cervical rib - Bifid rib
Osteochondrodysplasia	growth of tubular bones and spine: Achondrogenesis - Thanatophoric dysplasia - Short rib-polydactyly syndrome - Chondrodysplasia punctata (Rhizomelic chondrodysplasia punctata, Conradi-Hünermann syndrome), Achondroplasia (Hypochondroplasia, Osteosclerosis congenita) - Ellis-van Creveld syndrome - Spondyloepiphyseal dysplasia congenita Osteogenesis imperfecta - McCune-Albright syndrome - Osteopetrosis - Metaphyseal dysplasia - Hereditary multiple exostoses - Osteopoikilosis - Chondrodystrophy - Osteodystrophy
Other	abdominal wall (Congenital diaphragmatic hernia, Omphalocele, Gastroschisis, Prune belly syndrome) - Ehlers-Danlos syndrome
See also non-congenital conditions (M, 710-739)