International Classification of Diseases for Oncology
The International Classification of Diseases for Oncology (ICD-O) is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems for tumor diseases. This classification is widely used by cancer registries.
It is currently in its third revision.
Additional recommended knowledge
Axes
The classification has two axes:
Morphology
The morphology axis is for the morphology of the tumor.
This axis has additional importance, because the Systematized Nomenclature of Medicine has adopted ICD-O's classification of morphology.
Examples of codes
(8000-8009) Not otherwise specified
(8010-8790) Epithelial
- (8800-8809) Soft tissue Tumors And Sarcomas, Nos
- (8930-8990) Complex Mixed And Stromal Neoplasms
- (9000-9030) Fibroepithelial Neoplasms
- (M9000/0) Brenner tumor, NOS
- (9040-9049) Synovial-Like Neoplasms
- (M9040/3) Synovial sarcoma, NOS
- (9060-9090) Germ cell Neoplasms
- (9170-9179) Lymphatic vessel tumors
- (M9170/0) Lymphangioma, NOS
- (M9173/0) Cystic lymphangioma
- (9180-9240) Osseous And Chondromatous neoplasms
- (9250-9259) Giant cell tumors
- (9260-9269) Miscellaneous bone tumors
- (9270-9340) Odontogenic tumors
- (9350-9370) Miscellaneous tumors
- (9580-9589) Granular cell tumors and Alveolar soft part sarcoma
(9590-9999) Hematologic (Leukemias, Lymphomas and related disorders)
- (9590-9599) Malignant lymphoma, NOS, Or diffuse
- (9670-9680) Malignant lymphoma Specified Type, Diffuse Or Nos
- (9690-9699) Malignant lymphoma, Follicular Or Nodular, With Or Without diffuse areas
- (9730-9739) Plasma cell tumors
- (9740-9749) Mast cell Tumors
- (M9740/1) Mastocytoma, NOS or Extracutaneous mastocytoma
- (M9740/3) Mast cell sarcoma
- (M9741/1) Malignant mastocytosis or Indolent systemic mastocytosis
- (M9741/3) Aggressive systemic mastocytosis or Systemic mastocytosis with associated clonal, hematological non-mast cell lineage disease
- (M9742/3) Mast cell leukemia
- (M9751/1) Langerhans cell histiocytosis
- (M9755/3) Histiocytic sarcoma
- (M9756/3) Langerhans cell sarcoma
- (M9757/3) Dendritic cell sarcoma, NOS or Interdigitating dendritic cell sarcoma/tumor
- (M9758/3) Follicular dendritic cell sarcoma/tumor
-- Lymphoid leukemias, and related conditions
- (9800-9809) Leukemias, NOS
- (M9800/3) Leukemia, NOS
- (M9805/3) Acute leukemia of ambiguous lineage
- (M9801/3) Acute leukemia, NOS
-- Myeloid leukemias, and related conditions
- (9890-9899) Monocytic leukemias
- (M9890/3) Monocytic leukemia, NOS (FAB-M5)
- (M9891/3) Acute monoblastic and monocytic leukemia (FAB M5)
- (M9895/3) Acute myeloid leukemia multilineage dysplasia
- (M9896/3) AML with t(8;21)(q22;q22), AML1/ETO
- (M9897/3) AML with 11q23 (MLL) abnormalities
-- Other
Topography
The topography axis is for the topographical codes of the tumor's site. It is standardized with the C section of ICD-10
There were no changes in the topography axis between ICD-O-2 and ICD-O-3.
See List of ICD-10 codes#.28C00-C97.29 Malignant Neoplasms for examples.
See also
Morphology
- Cancer.gov - overview, includes link to Excel spreadsheet with codes at National Cancer Institute
- Overview at National Cancer Institute
- Word document - malignancies only at National Cancer Institute
- Overview at University hospital Gießen und Marburg
- Download table at DIMDI
- Codes at IARC
- 1st, 2nd, and 3rd editions at wolfbane.com
- List at The National Cancer Registry Ireland
- List at London School of Hygiene & Tropical Medicine
Hematological malignancy histology (ICD-O 9590-9989) |
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Lymphomas (9590-9759) | Hodgkin's lymphoma vs. Non-Hodgkin lymphoma - Diffuse lymphoma vs. Follicular lymphoma
B-cell lymphoma (Small cell, Primary effusion, Diffuse large, ,Burkitt's, Splenic marginal zone, MALT)
T-cell lymphoma (Cutaneous , Mycosis fungoides/Sézary's disease, Angioimmunoblastic, Anaplastic large cell, Hepatosplenic)
plasma cell (Plasmacytoma, Multiple myeloma)
mast cell tumor (Mast-cell sarcoma, Malignant mastocytosis, Malignant histiocytosis, Langerhans cell histiocytosis) |
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Immunoproliferative disorders (9760-9799) | Waldenström macroglobulinemia - Lymphomatoid granulomatosis |
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Lymphoid leukemias (9800-9839) | ALL - CLL - T-cell leukemia (Adult, Large granular lymphocyte, Prolymphocytic, Acute lymphoblastic) - B-cell leukemia (Prolymphocytic) |
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Myeloid leukemias (9840-9939, 9963) | AML (M2, APL/M3, AMoL/M5, Erythroleukemia/M6) - CML (CMoL, CNL, Philadelphia chromosome) - Granulocytic sarcoma |
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Other leukemias (9940-9949) | Hairy cell leukemia - Aggressive NK-cell leukemia |
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Myeloproliferative disease (9950-9961) | Polycythemia vera - Essential thrombocytosis - Myelofibrosis |
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Other (9964-9989) | Hypereosinophilic syndrome - Post-transplant lymphoproliferative disorder - Myelodysplastic syndrome |
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