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Homovanillic acid



Homovanillic acid
IUPAC name 2-(4-Hydroxy-3-methoxy-phenyl)acetic acid
Identifiers
CAS number 306-08-1
PubChem 1738
MeSH Homovanillic+acid
SMILES COC1=C(C=CC(=C1)CC(=O)O)O
Properties
Molecular formula C9H10O4
Molar mass 182.173
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)
Infobox disclaimer and references

Homovanillic acid (HOC6H3(OCH3)CH2COOH; synonyms: 3-Methoxy-4-hydroxyphenyl acetic acid; HVA; 4-Hydroxy-3-methoxy-benzeneacetic acid; 4-Hydroxy-3-methoxyphenylacetic acid) is a major catecholamine metabolite. It is used as a reagent to detect oxidative enzymes.

In psychiatry and neuroscience, brain and cerebrospinal fluid levels of HVA are measured as a marker of metabolic stress caused by 2-deoxy-D-glucose.1

Notes

  • Note 1: Marcelis M, Suckling J, Hofman P, Woodruff P, Bullmore E, van Os J. (2006) Evidence that brain tissue volumes are associated with HVA reactivity to metabolic stress in schizophrenia. Schizophr Res. 86(1-3):45-53. PMID 16806836
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Homovanillic_acid". A list of authors is available in Wikipedia.
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