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Hemodialysis product

Hemodialysis product (HDP) - is a number used to quantify hemodialysis and peritoneal dialysis treatment adequacy.

Additional recommended knowledge

Essential Laboratory Skills Guide

Weighing the right way

How to quickly check pipettes?

It was proposed by Scribner and Oreopoulous^[1] because of their perceived inadequacy of the Kt/V measure of dialysis adequacy. It has not been widely adopted.

The HDP is defined by the following empirical formula:

HDP = t * f ²

Where:

HDP - hemodialysis product
t - dialysis time (hours/dialysis session)
f - dialysis frequency (dialysis sessions/week)

The formula, like all empirical formulae, has no theoretical basis. The HDP has not seen widespread use.

References

^ Scribner BH, Oreopoulos DG, The Hemodialysis Product (HDP): A Better Index of Dialysis Adequacy than Kt/V, Dialysis & Transplantation, 2002 Jan;31(1):13-15. Full Text Full Text (Mirror)

v • d • e Urinary system, physiology: renal physiology and acid base physiology
Filtration	Renal blood flow - Ultrafiltration - Countercurrent exchange
Hormones affecting filtration	Antidiuretic hormone (ADH) - Aldosterone - Atrial natriuretic peptide
Secretion/clearance	Pharmacokinetics - Clearance of medications
Reabsorption	Solvent drag -Na⁺ - Cl^- -urea -glucose -oligopeptides -protein
Endocrine	Renin - Erythropoietin (EPO) - Calcitriol (Active vitamin D) - Prostaglandins
Assessing Renal function / Measures of dialysis	Glomerular filtration rate - Creatinine clearance - Renal clearance ratio - Urea reduction ratio - Kt/V - Standardized Kt/V - Hemodialysis product - PAH clearance (Effective renal plasma flow - Extraction ratio)
Acid base physiology	Fluid balance - Darrow Yannet diagram - Body water - Interstitial fluid - Extracellular fluid - Intracellular fluid/Cytosol - Plasma - Transcellular fluid - Base excess - Davenport diagram - Anion gap - Arterial blood gas
Buffering/compensation	Bicarbonate buffering system - Respiratory compensation - Renal compensation