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Hemodialysis product

Hemodialysis product (HDP) - is a number used to quantify hemodialysis and peritoneal dialysis treatment adequacy.

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It was proposed by Scribner and Oreopoulous^[1] because of their perceived inadequacy of the Kt/V measure of dialysis adequacy. It has not been widely adopted.

The HDP is defined by the following empirical formula:

HDP = t * f ²

Where:

HDP - hemodialysis product
t - dialysis time (hours/dialysis session)
f - dialysis frequency (dialysis sessions/week)

The formula, like all empirical formulae, has no theoretical basis. The HDP has not seen widespread use.

References

^ Scribner BH, Oreopoulos DG, The Hemodialysis Product (HDP): A Better Index of Dialysis Adequacy than Kt/V, Dialysis & Transplantation, 2002 Jan;31(1):13-15. Full Text Full Text (Mirror)

v • d • e Urinary system, physiology: renal physiology and acid base physiology
Filtration	Renal blood flow - Ultrafiltration - Countercurrent exchange
Hormones affecting filtration	Antidiuretic hormone (ADH) - Aldosterone - Atrial natriuretic peptide
Secretion/clearance	Pharmacokinetics - Clearance of medications
Reabsorption	Solvent drag -Na⁺ - Cl^- -urea -glucose -oligopeptides -protein
Endocrine	Renin - Erythropoietin (EPO) - Calcitriol (Active vitamin D) - Prostaglandins
Assessing Renal function / Measures of dialysis	Glomerular filtration rate - Creatinine clearance - Renal clearance ratio - Urea reduction ratio - Kt/V - Standardized Kt/V - Hemodialysis product - PAH clearance (Effective renal plasma flow - Extraction ratio)
Acid base physiology	Fluid balance - Darrow Yannet diagram - Body water - Interstitial fluid - Extracellular fluid - Intracellular fluid/Cytosol - Plasma - Transcellular fluid - Base excess - Davenport diagram - Anion gap - Arterial blood gas
Buffering/compensation	Bicarbonate buffering system - Respiratory compensation - Renal compensation