To use all functions of this page, please activate cookies in your browser.
my.bionity.com
With an accout for my.bionity.com you can always see everything at a glance – and you can configure your own website and individual newsletter.
- My watch list
- My saved searches
- My saved topics
- My newsletter
Helicobacter pylori eradication protocolsHelicobacter pylori eradication protocols is a standard name for all treatment protocols for peptic ulcers and gastritis, which primary goal is not only temporary relief of symptoms, but total elimination of Helicobacter pylori infection instead. Additional recommended knowledgeDefinitionA good, clinically useful H.pylori eradication protocol is a treatment protocol, which ensures at least 80% H. pylori eradication rate, is not longer than 14 days (preferably 7 or 10 days) and is not too toxic (side effects should occur in not more than 10-15% patients receiving treatment by this protocol, and should not be so severe to warrant treatment discontinuation). The treatment regimen should also be easy to follow by the patient, to improve or maintain high rate of treatment compliance. During last decades, several new eradication protocols have been developed. This allowed clinicians to target several goals:
History of H. pylori eradication protocolsOne of the first "eradication protocols", if not the first, was the protocol used by Barry Marshall to treat his own gastritis, which developed following intentional ingestion of H. pylori culture. He used bismuth salt and metronidazole. This treatment effectively cured his gastritis and eliminated the H. pylori infection. But in terms of modern eradication protocol definition, which requires not only occasional ability to cure the infection, but at least 80% eradication rate, this protocol cannot be described as "eradication protocol" and is not clinically reasonable. One of the first "modern" eradication protocols, which is still used today, is a one week triple therapy. The Sydney gastroenterolgist Thomas Borody invented the first triple therapy in 1987.[1] Today, the standard triple therapy is amoxicillin, clarithromycin and a proton pump inhibitor such as omeprazole.[2] Links
|
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Helicobacter_pylori_eradication_protocols". A list of authors is available in Wikipedia. |