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HLA-B*82




major histocompatibility complex (human), class I, B82
Alleles	B8201 B8202
Structure (See HLA-B)
Symbol(s)	HLA-B
EBI-HLA	B*8201
EBI-HLA	B*8202
Locus	chr.6 6p21.31

HLA-B*82 (B*82) is an HLA-B allele-group. There is no current useful serotyping for HLA-B*82 gene products.^[1] B*8201 was first identified by sequence analysis and appears to be derived by gene conversion between B*5602 and another HLA class I allele.^[2], later B*8202 was identified in a caucasian and was suggested to be ancestral to B*8201, as product between gene conversion of B*5602 allele and B*4501 allele. B*82 is more common in East Africa, Kenya and Sudan, the frequency of B*8201 is found in the peoples to the west, sporadically in Central and West Africa, B*8202 is found in Sudan and Saudi Arabia.^[3]

Additional recommended knowledge

Serotype

B82 serotype recognition of Some HLA B*82 allele-group gene products^[4]
B*82	B82	other	Sample
allele	%	%	size (N)
8201	3	79	146

Allele frequencies

**HLA B*8201 frequencies**
		freq
ref.	Population	(%)
^[5]	Luo (Kenya)	1.9
^[5]	Guinea Bissau	0.8
^[5]	Natal Zulu (S. Africa)	0.5
^[5]	Beti (Cameroon)	0.3
^[5]	Kenya	0.3
^[5]	Kampala (Uganda)	0.3
^[5]	Nandi (Kenya)	0.2
'
*HLA B8202 frequencies**
^[5]	Sudanese	2.5
^[5]	Kenya	0.7
^[5]	Guraiat and Hail (Saudi Arabia)	0.2

References

^ Marsh SG, Albert ED, Bodmer WF, et al (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMID 15787720.
^ Hurley CK, Steiner N, Hoyer RJ, et al (1996). "Novel HLA-B alleles, B*8201, B*3515 and B*5106, add to the complexity of serologic identification of HLA types". Tissue Antigens 47 (3): 179–87. PMID 8740766.
^ Cox ST, Hossain E, McWhinnie A, Prokupek B, Madrigal JA, Little AM (2000). "HLA-B*8202 identified in a Caucasoid potential bone marrow donor". Tissue Antigens 56 (2): 188–91. PMID 11019925.
^ derived from IMGT/HLA
^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens 61 (5): 403-7. PMID 12753660.

v • d • e HLA-B Serotypes and allele groups
HLA-B - B5 (B51 - B52) - B7 - B8 - B12 (B44 - B45) - B13 - B14 (B64 - B65) - B15 (B62 - B63 - B70 - B71- B75 - B76 - B77) - B16 (B38 - B39) - B17 (B57 - B58) - B18 - B21 (B49 - B50) - B22 (B54 - B55 - B56) - B27 - B35 - B37 - B40 (B60 - B61) - B41 - B42 - B46 - B47 - B48 - B53 - B59 - B67 - B73 - B78 - B81 - *B82** - B*83