My watch list

HLA-A74




major histocompatibility complex (human), class I, A74
Alleles	A7401 A7403
Structure (See HLA-A)
Identifiers	7401 7403
Symbol(s)	HLA-A
EBI-HLA	A*7401
EBI-HLA	A*7403
Shared data
Locus	chr.6 6p21.31

HLA-A74 (A74) is an HLA-A serotype. The serotype identifies the HLA-A*7401 gene product. A74 is a split antigen type of the A19 broad antigen type. A74 is rare.

Additional recommended knowledge

How to ensure accurate weighing results every day?

How to quickly check pipettes?

Don't let static charges disrupt your weighing accuracy

1 Serotype
- 1.1 Disease associations
2 A*74 allele Frequencies
3 References

Serotype

A74, A19 serotype recognition of Some HLA A*74 allele-group gene products^[1]
A*74	A74	A19	Sample
allele	%	%	size (N)
7401	40	11	119
7401	17		29

Disease associations

A significant association has been found between A74 and nasal polyposis.^[2]

A*74 allele Frequencies

HLA A*7401 frequencies
		freq
ref.	Population	(%)
^[3]	Kenya	9.7
^[3]	Cameroon Beti	8.3
^[3]	Guinea Bissau	7.7
^[3]	Burkina Faso Mossi	6.6
^[3]	Uganda Kampala	5.2
^[3]	Cameroon Yaounde	5.0
^[3]	Cameroon Bamileke	4.5
^[3]	Cameroon Sawa	3.8
^[3]	Mali Bandiagara	3.6
^[3]	Iran Baloch	2.8
^[3]	Zimbabwe Harare Shona	2.7
^[3]	Senegal Niokholo Mandenka	2.2
^[3]	Burkina Faso Rimaibe	2.1
^[3]	Kenya Nandi	1.7
^[3]	Morocco Nador Metalsa	1.4
^[3]	Thailand Northeast	1.2
^[3]	Thailand	1.1
^[3]	Jordon Amman	0.7
^[3]	Jordon Amman	0.5
^[3]	China South	0.5

HLA A*7403 frequencies
		freq
ref.	Population	(%)
^[3]	Kenya Luo	7.3
^[3]	Iran Baloch	0.6
^[3]	Kenya	0.3
^[3]	Uganda Kampala	0.3

References

^ derived from IMGT/HLA
^ Luxenberger W, Posch U, Berghold A, Hofmann T, Lang-Loidolt D (2000). "HLA patterns in patients with nasal polyposis". European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 257 (3): 137–9. PMID 10839486.
^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l ^m ⁿ ^o ^p ^q ^r ^s ^t ^u ^v ^w ^x Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens 61 (5): 403-7. PMID 12753660.

v • d • e HLA-A Serotypes
HLA-A - A1 - A2 - A3 - A9 (A23 - A24) - A10 (A25 - A26 - A34 - A43 - A66) - A11 - A19 (A29 - A30 - A31 - A32 - A33 - A74) - A28 (A68 - A69) - A36 - A80

Category: HLA-A alleles

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "HLA-A74". A list of authors is available in Wikipedia.