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HLA-A25
HLA-A25 (A25) is an HLA-A serotype. The serotype identifies the more common HLA-A*25 gene products. A25 is a split antigen of the A10 broad antigen serotype group. It is believed to have been formed by a single gene conversion between another HLA-A and the A*2601 allele.[1] A26 is more common in Western Europe. Additional recommended knowledge
Serotype
There are 7 alleles for A25, 6 that result in different isoforms. A25 frequencies
A*2501 distribution is primarily located in western Eurasia. Frequency tends to be highest in the populations that underwent later neolithization suggesting A*2501 spread in Europe. The high frequency in Saudi Arabia is suggestive of a source.
References
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This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "HLA-A25". A list of authors is available in Wikipedia. |