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Glycerol 3-phosphate



Glycerol 3-phosphate
IUPAC name 1,2,3-Propanetriol, 1- (dihydrogen phosphate)
Other names
Glycerol-1-phosphate
Glycerophosphate
α-glycerolphosphate
Identifiers
CAS number 57-03-4
PubChem 754
MeSH glycerol+3-phosphate
SMILES OCC(O)COP(O)(O)=O
Properties
Molecular formula C3H9O6P
Molar mass 172.074
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)
Infobox disclaimer and references


Glycerol 3-phosphate is a chemical intermediate in the glycolysis metabolic pathway. It should not be confused with the similarly named glycerate 3-phosphate or glyceraldehyde 3-phosphate.

Function

Gylcerol 3-phosphate is produced from glycerol, the triose sugar backbone of triglycerides and glycerophospholipids, by the enzyme glycerol kinase. Glycerol 3-phospate may then be converted by dehydrogenation to dihydroxyacetone phosphate (DHAP) by the enzyme glycerol-3-phosphate dehydrogenase. DHAP can then be rearranged into glyceraldehyde 3-phosphate(GA3P) by triose phosphate isomerase(TIM), and feed into glycolysis.

The glycerol 3-phosphate shuttle is used to rapidly regenerate NAD+ in brain and skeletal muscle cells of mammals.

See also

  • Glycerol-3-phosphate dehydrogenase
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Glycerol_3-phosphate". A list of authors is available in Wikipedia.
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