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Fetal trimethadione syndromeFetal trimethadione syndrome (also known as paramethadione syndrome, German syndrome, tridione syndrome, among others[1]) is a set of birth defects caused by the administration of the anticonvulsants trimethadione (also known as Tridione) or paramethadione to epileptic mothers during pregnancy.[2] Additional recommended knowledgeFetal trimethadione syndrome is classified as a rare disease by the National Institute of Health's Office of Rare Diseases,[3] meaning it affects less than 200,000 individuals in the United States.[4] The fetal loss rate while using trimethadione has been reported to be as high as 87%.[5] CharacteristicsFetal trimethadione syndrome is characterized by the following major symptoms as a result of the teratogenic characteristics of trimethadione.[6][7]
References
Categories: Syndromes | Rare diseases |
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Fetal_trimethadione_syndrome". A list of authors is available in Wikipedia. |