Extraglomerular mesangial cell

Extraglomerular mesangial cells (or lacis cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.

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Lacis cells form the juxtaglomerular apparatus in combination with two other types of cells: the macula densa of the thick ascending limb of Henle and Juxtaglomerular cells of the afferent arteriole. This apparatus controls blood pressure through the Renin-Angiotensin-Aldosterone system. The specific function of Lacis cells is not well understood. Although is it has been associated with the secretion of Erythropoietin. ^[1]

References

^ Junqueira, Luiz C.; Jose Carneiro (2003). Basic Histology. McGraw-Hill. ISBN 0838505902.

v • d • e Urinary system - Kidney
Layers	Renal fascia • Renal capsule • Renal cortex (Renal column) • Renal medulla (Renal sinus, Renal pyramids, medullary interstitium) • Renal lobe • Cortical lobule • Medullary ray • Nephron
Afferent circulation	Renal artery → Segmental arteries → Interlobar arteries → Arcuate arteries → Cortical radial arteries → Afferent arterioles → Renal corpuscle (Glomerulus, Bowman's capsule)
Renal tubule	Proximal tubule → Loop of Henle (Descending, Thin ascending, Thick ascending) → Distal convoluted tubule → Connecting tubule → Collecting ducts → Duct of Bellini → Renal papilla → Minor calyx → Major calyx → Renal pelvis → Ureter
Efferent circulation	Glomerulus → Efferent arterioles → Peritubular capillaries/Vasa recta → Arcuate vein → Interlobar veins → Renal vein
Juxtaglomerular apparatus	Macula densa • Juxtaglomerular cells • Extraglomerular mesangial cell
Filtration	Glomerular basement membrane • Podocyte • Filtration slits • Intraglomerular mesangial cell • Tubular fluid
Renal physiology	Acid base physiology • Fluid balance