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Esterase

An esterase is a hydrolase enzyme that splits esters into an acid and an alcohol in a chemical reaction with water called hydrolysis.

A wide range of different esterases exist that differ in their substrate specificity, their protein structure, and their biological function.

EC classification/list of enzymes

- Acetylesterase (EC 3.1.1.6), splits off acetyl groups
  - Cholinesterase
    - Acetylcholinesterase, inactivates the neurotransmitter acetylcholine
    - Pseudocholinesterase, broad substrate specificity, found in the blood plasma and in the liver
- Pectinesterase (EC 3.1.1.11), clarifies fruit juices

EC 3.1.2: Thiolester hydrolases
- Thioesterase
  - Ubiquitin carboxy-terminal hydrolase L1

Exonucleases (deoxyribonucleases and ribonucleases)
- EC 3.1.11: Exodeoxyribonucleases producing 5'-phosphomonoesters
- EC 3.1.13: Exoribonucleases producing 5'-phosphomonoesters
- EC 3.1.14: Exoribonucleases producing 3'-phosphomonoesters
- EC 3.1.15: Exonucleases active with either ribo- or

v • d • e Proteins: enzymes
Topics	Active site - Allosteric regulation - Binding site - Catalytically perfect enzyme - Coenzyme - Cofactor - Cooperativity - EC number Enzyme catalysis - Enzyme inhibitor - Enzyme kinetics - Lineweaver-Burk plot - Michaelis-Menten kinetics - List of enzymes
Types	EC1 Oxidoreductases/list - EC2 Transferases/list - EC3 Hydrolases/list - EC4 Lyases/list - EC5 Isomerases/list - EC6 Ligases/list

v • d • e Hydrolase: esterases (EC 3.1)
3.1.1: Carboxylic ester hydrolases	Cholinesterase - Pectinesterase - 6-phosphogluconolactonase - PAF acetylhydrolase Lipase (Gastric/Lingual, Pancreatic, Lysosomal, Hormone-sensitive, Endothelial, Hepatic, Lipoprotein, Monoacylglycerol, Diacylglycerol) Phospholipase (A1, A2, B)
3.1.2: Thioesterase	Palmitoyl thioesterase - Ubiquitin carboxy-terminal hydrolase L1
3.1.3: Phosphatase	Alkaline phosphatase - Acid phosphatase (Prostatic)/Tartrate resistant acid phosphatase/Purple acid phosphatases - Nucleotidase - Glucose 6-phosphatase - Fructose 1,6-bisphosphatase - Calcineurin - Phosphoprotein phosphatase (PP2A) - OCRL - Pyruvate dehydrogenase phosphatase - Fructose 2,6-bisphosphatase - Protein tyrosine phosphatase - PTEN
3.1.4: Phosphodiesterase	Autotaxin - Phospholipase (C, D) - Sphingomyelin phosphodiesterase - PDE1 - PDE2 - PDE3 - PDE5
3.1.6: Sulfatase	Arylsulfatase B - Steroid sulfatase - Galactosamine-6 sulfatase - Arylsulfatase A - Iduronate-2-sulfatase - N-acetylglucosamine-6-sulfatase
other	Nuclease

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Esterase". A list of authors is available in Wikipedia.