ENU

  ENU, also known as N-ethyl-N-nitrosourea (chemical formula C₃H₆N₃O₂), is a highly potent mutagen. For a given gene in mice, ENU can induce 1 new mutation in every 700 gametes. It is also toxic at high doses.

Additional recommended knowledge

What is the Correct Way to Check Repeatability in Balances?

Daily Sensitivity Test

Weighing the right way

The chemical is an alkylating agent, and acts by transferring the ethyl group of ENU to nucleobases (usually thymine) in nucleic acids. Its main targets are the spermatogonial stem cells, from which mature sperm are derived.