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Dopamine agonist



  A dopamine agonist is a compound that activates dopamine receptors, mimicking the effect of the neurotransmitter dopamine.

Contents

Uses

Some medical drugs act as dopamine agonists; they are typically used for treating Parkinson's disease and certain Pituitary tumors (prolactinomas), and may be useful for restless legs syndrome (RLS). Both Requip (Ropinirole) and Mirapex (Pramipexole) are FDA approved for the treatment of RLS.

There is also an ongoing clinical trial to test the effectiveness of Requip (Ropinirole), a dopamine agonist, in reversing the symptoms of SSRI induced sexual dysfunction. [1]

Examples

Examples of dopamine agonists include:

See also

References

  1. ^ ClinicalTrials.gov NCT00334048 - "Treating Sexual Dysfunction From SSRI Medication: a Study Comparing Requip CR to Placebo"
  2. ^ http://www.fda.gov/bbs/topics/NEWS/2007/NEW01596.html
v • d • e
Anti-parkinson drugs: dopaminergic agents (N04B)
Dopa and derivativesLevodopa, Melevodopa, Etilevodopa
Adamantane derivativesAmantadine
Dopamine agonistsApomorphine, Bromocriptine, Cabergoline, Dihydrexidine, Dihydroergocryptine mesylate, Fenoldopam, Lisuride, Pergolide, Piribedil, Pramipexole, Quinpirole, Ropinirole, Rotigotine, SKF 38393, SKF 82958
MAOIsSelegiline, Rasagiline
OtherTolcapone, Entacapone, Budipine
v • d • e
Receptor agonists and antagonists (and reuptake inhibitors)
Dopamine receptorDopamine agonist - Dopamine antagonist - Dopamine reuptake inhibitor
5-HT (serotonin) receptorSerotonin receptor agonist - Serotonin antagonist (5-HT3 antagonist) - Serotonin uptake inhibitor (SSRI)
Adrenergic receptoradrenergic agonist (Adrenergic alpha-agonist, Beta2-adrenergic receptor agonist) - adrenergic antagonist (Alpha blocker, Beta blocker) - Adrenergic uptake inhibitor
Acetylcholine receptorcholinergic (Muscarinic agonist, Nicotinic agonist) - anticholinergic (Muscarinic antagonist, Nicotinic antagonist) - Acetylcholinesterase inhibitor
Histamine receptorHistamine agonist - Histamine antagonist (H1, H2)
GABA receptorGABA agonist - GABA antagonist
NMDA receptorNMDA antagonist
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Dopamine_agonist". A list of authors is available in Wikipedia.
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