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Diphenylamine as building blocker of Mannich bases



It is used as building blockers to form Mannich bases which are the most important pharmaceutical components as well as the products of industrial importance.Many research papers has been published regarding it to show the potentialities of it in building Mannich bases.

Diphenylamine
IUPAC name Diphenylamine
Other names N-Phenylbenzenamine;
N-Phenyl Aniline;
DPA;
Anilinobenzene;
(phenylamino)benzene;
N,N-diphenylamine;
big dipper;
C.I. 10355;
Phenylbenzenamine;
Diphenylamine;
Identifiers
CAS number 122-39-4
RTECS number 9
SMILES c1ccccc1Nc2ccccc2
Properties
Molecular formula C12H11N
Molar mass 169.23 g/mol
Appearance White to yellow crystals
Density 1.2 g/cm³
Melting point

53 °C (326 K)

Boiling point

302 °C (575 K)

Solubility in water Slightly
Hazards
Main hazards Toxic. Possible mutagen. Possible teratogen. Harmful in contact with skin, and if swallowed or inhaled. Irritant.
NFPA 704
1
3
0
 
R-phrases R23 R24 R25 R33 R50 R53
S-phrases S36 S37 S45 S60 S61
Flash point 152°C
Related Compounds
Related Amine Aniline
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)
Infobox disclaimer and references

Diphenylamine is an aromatic amine with the structural formula (C6H5)2NH. It has been used for scald control on apples in the United States, and it is a fungicide.

It has been used in a test for nitrates [1]

One synthesis is the reaction of aniline to form a mixture of ammonia and diphenyl amine.

It is considered to be and is known to be toxic and harmful to the environment.

It also finds use in DNA detection. See DNA extraction.

DNA Quantification Using Dimethylamine (click on PDF download link)

References

     
    This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Diphenylamine_as_building_blocker_of_Mannich_bases". A list of authors is available in Wikipedia.
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