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Dalbavancin

Dalbavancin
Identifiers
CAS number
PubChem	16134410
Properties
Molecular formula	C₈₈H₁₀₀Cl₂N₁₀O₂₈
Molar mass	1816.6918
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

Dalbavancin, a novel second-generation lipoglycopeptide agent, belongs to the same class as vancomycin, the most widely-used and one of the few treatments available to patients infected with MRSA.^[1]

Additional recommended knowledge

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It possesses in vitro activity against a variety of gram-positive pathogens^[2]^[3] including MRSA and MRSE. ^[4]It is a once-weekly, two-dose antibiotic that Pfizer acquired when it bought Vicuron Pharmaceuticals in 2005.^[5]

References and notes

^ Vicuron Pharmaceuticals Submits New Drug Application for Dalbavancin to U.S. Food and Drug Administration
^ Chen AY, Zervos MJ, Vazquez JA (2007). "Dalbavancin: a novel antimicrobial". Int. J. Clin. Pract. 61 (5): 853–63. doi:10.1111/j.1742-1241.2007.01318.x. PMID 17362476.
^ Das B, Sarkar C, Biswas R, Pandey S (2008). "Review: dalbavancin-a novel lipoglycopeptide antimicrobial for gram positive pathogens". Pak J Pharm Sci 21 (1): 78–88. PMID 18166524.
^ Dalbavancin: A Novel Lipoglycopeptide Antibacterial
^ UPDATE 1-Pfizer says US FDA wants more data on antibiotic

v • d • e Antibacterials for systemic use: others (J01X)
Glycopeptide	Vancomycin - Teicoplanin
Polymyxins	Colistin - Polymyxin B
Steroid antibacterials	Fusidic acid
Imidazole derivatives	Metronidazole - Tinidazole - Ornidazole
Nitrofuran derivatives	Nitrofurantoin - Nifurtoinol
Other	Fosfomycin - Xibornol - Clofoctol - Spectinomycin - Methenamine - Mandelic acid - Nitroxoline - Linezolid - Daptomycin - Hitachimycin - Dalbavancin - Telavancin