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Cl-formate exchanger

The Cl-formate exchanger is a transport protein present in the kidney^[1], where it functions in the renal chloride reabsorption. It is also present in vascular smooth muscle and cardiac muscle ^[2].

The true molecular nature of the protein is unknown^[3].

References

^ Chloride/Formate Exchange with Formic Acid Recycling: A Mechanism of Active Chloride Transport across Epithelial Membranes Lawrence P. Karniski and Peter S. Aronson
^ [Presence of chloride-formate exchange in vascular smooth muscle and cardiac cells M Soleimani and RL Howard. Department of Medicine, Indiana University School of Medicine, Indianapolis 46202-5116.
^ renal proximal tubule cells Identification of a chloride-formate ...

v • d • e Membrane proteins, carrier proteins: membrane transport proteins
ABC-transporter	A1, A2, A4, A12, B1, B2-3, B4, B5, B11, C1, C2, C4, C5, C6, C8, C8-9, C11, D1, D3, E1, G1, G2, G5, G8
Solute carrier	1A1-7, 1A1, 1A2, 1A3, 1A5, 2A1, 2A2, 2A3, 2A4, 3A1, 3A2, 4A1, 4A4, 4A7, 5A1-2, 5A5, 6A1, 6A2, 6A3, 6A8, 6A4, 7A5, 7A9, 8A1-3, 9A1, 9A3, 10A2, 11A1, 11A2, 11A3, 12A1-2, 12A3, 15A1, 17A5, 17A6-8, 18A1, 18A2, 18A3, 19A1, 19A2, 19A3, 22A1, 22A2, 22A3, 22A4, 22A5, 22A6, 23A1, 23A2, 24A1-2, 24A5, 25A4-6, 25A8, 25A13, 25A15, 25A20, 26A2, 26A3, 26A4, 29A1, 29A2, 30A8, 31A1, 31A2, 34A1, 37A4, 39A4, 40A1, O1B1
Monosaccharide	GLUT1, GLUT2, GLUT3, GLUT4, GLUT5, GLUT8
Other	Amino acid (CD98) - Fatty acid (CD36) - Ion channels - Ion pumps - Mitochondrial membrane transport protein - Neurotransmitter transport proteins - Nuclear (Karyopherin)

v • d • e Membrane transport protein: ion pumps
Symporter, Cotransporter	Na+/K+/2Cl- - Na/Pi3 - Na+/Cl- - Na/glucose - Na+/I- - Cl-/K+ (4, 5)
Antiporter (exchanger)	Na+/H+ - Na+/Ca2+ (Na+/(Ca2+-K+)) - Cl-/HCO3- (Band 3) - Cl-formate exchanger - Cl-oxalate exchanger
ATPase	Cu++ - Ca+ (SERCA-ATP2A2, Plasma membrane) - Na+/K+ - H+/K+ - ATP synthase - H+ (F-type) - H+ (V-type)
Other	Uniporter - Halorhodopsin - Proton pump