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Cicutoxin
Cicutoxin (chemical name: (8E,10E,12E,14R)-heptadeca-8,10,12-trien-4,6-diyne-1,14-diol; formula: C17H22O2) is a poisonous polyyne and alcohol found in various plants, most notably water hemlock. It is structural related to the oenanthotoxin of hemlock water dropwort. Additional recommended knowledgeIt is a cholinergic poison, causing death by disruption of the central nervous system. It is a potent, noncompetitive gamma-aminobutyric acid (GABA) receptor antagonist. In humans, cicutoxin rapidly produces symptoms of nausea, emesis and abdominal pain, typically within 60 minutes of ingestion. This can lead to tremors and seizures. References
Categories: Neurotoxins | Plant toxins |
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This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Cicutoxin". A list of authors is available in Wikipedia. |