Caudal regression syndrome

Caudal regression syndrome is a rare disorder in which there is abnormal fetal development of the lower spine.

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Presentation

It can lead to a variety of problems ranging from partial absence of the tail bone regions of the spine to more severe cases involving major malformation of the lower vertebrae, pelvis and spine. Minor cases may be more or less without symptom, whereas severe cases may come with major birth defects, neurological impairment and incontinence.

Associations

It can be associated with maternal diabetes.^[1]

Synonyms

Synonyms for CRS:

• Caudal Dysplasia
• Caudal Dysplasia Sequence
• Sacral Agenesis, Congenital
• Sacral Regression

See also

• Sacral agenesis
• Sirenomelia

References

1. ^ Fayyaz A, Ilyas M, Iqbal O (2007). "Pre-natal diagnosis of caudal regression syndrome". Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 17 (7): 425–6. doi:07.2007/JCPSP.425426. PMID 17686358.