cation channel, sperm associated 1
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Identifiers
|
Symbol
| CATSPER1
|
Entrez
| 117144
|
HUGO
| 17116
|
OMIM
| 606389
|
RefSeq
| NM_053054
|
UniProt
| Q8NEC5
|
Other data
|
Locus
| Chr. 11 q12.1
|
cation channel, sperm associated 2
|
Identifiers
|
Symbol
| CATSPER2
|
Entrez
| 117155
|
HUGO
| 18810
|
OMIM
| 607249
|
RefSeq
| NM_172097
|
UniProt
| Q96P55
|
Other data
|
Locus
| Chr. 15 q13-q15
|
cation channel, sperm associated 3
|
Identifiers
|
Symbol
| CATSPER3
|
Entrez
| 347732
|
HUGO
| 20819
|
OMIM
| 609120
|
RefSeq
| NM_178019
|
UniProt
| Q86XQ3
|
Other data
|
Locus
| Chr. 5 q31.2
|
cation channel, sperm associated 4
|
Identifiers
|
Symbol
| CATSPER4
|
Entrez
| 378807
|
HUGO
| 23220
|
OMIM
| 609121
|
RefSeq
| XM_371237
|
UniProt
| Q7RTX7
|
Other data
|
Locus
| Chr. 1 p35.3
|
Cation channels of sperm: This small family of ion channels, normally referred to as Catsper channels or CatSper, is related to the two-pore channels and distantly related to TRP channels. The four members of this family form voltage-gated Ca2+ channels that seem to be specific to sperm. These channels are required for proper fertilization. The study of these channels has been slow because they do not traffic to the cell membrane in many heterologous systems.
See also
Membrane transport protein: ion channels |
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Ca2+: Calcium channel | Voltage-dependent calcium channel (L-type/Cavα(1.1, 1.2, 1.3, 1.4), N-type, P-type/Cavα(2.1), Q-type, R-type, T-type, β-subunits (β1, β2, β4), γ-subunits (γ2) • Inositol triphosphate receptor • Ryanodine receptor • Cation channels of sperm • Two-pore channel |
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Na+: Sodium channel | Navα (1.1, 1.2, 1.4, 1.5, 1.7, 1.9) • Navβ (1, 3, 4) • Epithelial sodium channel |
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K+: Potassium channel | Voltage-gated (Kvα (1.1, 1.2, 1.3, 1.4, 1.5, 2.1, 4.2, 4.3, 7.1, 7.2, 7.3, 7.4, 10.1, 11.1/hERG) • Kvβ (1, 2), Shaker gene, KCNE1) • Calcium-activated (BK channel, SK channel, SK3) • Inward-rectifier Kir (1.1, 2.1, 2.2, 2.3, 3.1, 3.2, 3.4, 4.1, 4.2, 6.1, 6.2)) • Tandem pore domain K2P (1, 2, 3, 4, 6, 9) |
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Cl-: Chloride channel | Cystic fibrosis transmembrane conductance regulator |
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Porin | Aquaporin (1, 2, 3, 4) • Voltage-dependent anion channel (1) |
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Cations: TRP | TRPA (1) • TRPC (1, 2, 3, 4, 4AP, 5, 6, 7) • TRPM (1, 2, 3, 4, 5, 6, 7, 8) • TRPML (Mucolipin-1) • TRPP (1, 2)• TRPV (1, 2, 3, 4, 5, 6) |
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Other/general | Voltage-gated ion channel • Ligand-gated ion channel • Cyclic nucleotide-gated ion channel (α1, α3, β3, H1, H2, H4) • Stretch-activated ion channel |
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