Bioprocessing Technology Institute

The Bioprocessing Technology Institute (BTI) is a national institute in Singapore funded by the Agency for Science, Technology and Research (A*STAR) through its Biomedical Research Council. BTI spearheads bioprocess science and engineering research by combining molecular biology, biochemistry, proteomic and genomic sciences, to understand how to enhance the productivity of cells, develop better cell culture, fermentation and separation processes to manufacture important molecules such as antibodies, recombinant DNA and proteins that target a myriad of diseases.

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To advance cell-based therapeutics, researchers in BTI customise culture conditions, optimise media, identify reactors and purification procedures unique to the target cells. BTI also engages in research collaborations leading to proprietary technologies with local and overseas companies and universities.

Miranda Yap is as of 2006, the Executive Director of the Institute.

BTI's current areas of research are:

• Cellular expression engineering
• Animal cell technology
• Microbial fermentation
• Stem cell research
• Downstream processing and analytics
• Microarray and proteomics

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