Interferon beta-1b

Interferon beta-1b (marketed as Betaseron) is a drug in the interferon family used to treat the relapsing-remitting form of multiple sclerosis. It is administered by sub-cutaneous injection and has been shown to slow the advance of the affliction as well as reduce the frequency of attacks. Betaseron is manufactured by Berlex Corporation.

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It is believed that Interferon-Beta based drugs achieve their beneficial effect on MS progress via their anti-inflammatory properties. Studies have also determined that Interferon-Beta improves the integrity of the blood-brain barrier (BBB)—which generally breaks down in MS patients, allowing increasing amounts of undesirable substances to reach the brain. This strengthening of the BBB may be a contributing factor to Interferon-Beta's beneficial effects. These studies were carried out in vitro, so it does not necessarily mean it works the same in people.

Closely related is Interferon beta-1a, also indicated for multiple sclerosis, and with a very similar drug profile.

See also

• Interferon beta-1a
• Multiple sclerosis