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Andes virus



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Please help improve this article by adding reliable references. Unsourced material may be challenged and removed. (December 2007)
Andes virus
Virus classification
Group: Group V ((-)ssRNA)
Family: Bunyaviridae
Genus: Hantavirus
Species: Andes virus

Andes virus (ANDV) is a hantavirus, which, in South America, is a major causative agent of Hantavirus Cardiopulmonary Syndrome (HCPS or HPS).

Background

HCPS due to the Andes virus infection, has a case fatality percentage of about 25-35% in Argentina[1] and of 37% in Chile.[2] ANDV, lineage ANDV-Sout, is the only hantavirus for which a person-to-person transmission has been described.[3][4][5] Several ANDV strains are co-circulating in Argentina, e.g. Bermejo, Lechiguanas, Maciel, Oran and Pergamino[6], whereas HCPS cases were also reported in Bolivia, Brazil, Paraguay and Uruguay. Only for Chile and Argentina can they be strictly associated with ANDV.

In Argentina and Chile, the long-tailed rice rat, Oligoryzomys longicaudatus, and other species of the genus Oligoryzomys represent the reservoir for ANDV.[7][8][9] Another unique characteristic of ANDV is the availability of an animal model. ANDV causes lethal disease in the Syrian Hamster that closely models the course of disease progression in humans, including a rapid progression from first symptoms to death, including fluid in the pleural cavity and the histopathology of the lungs and spleen. [10] Lethality of ANDV in hamsters is not true of all HCPS viruses, as challenge with Sin Nombre virus shows no symptoms of disease.[10] The availabilty of this model allows for the study of various drugs and other treatments that may have an impact on the treatment of all HCPS-causing hantavirus infections.

See also

References

  1. ^ Paula Padula. "Personal Communication", Buenos Aires. 
  2. ^ Government of Chile. "Ministry of Health, 2005". 
  3. ^ Padula et al. "2005, 1998". 
  4. ^ Toro et al. "1998". 
  5. ^ Wells et al. "1998". 
  6. ^ Padula et al. "2000, 2002". 
  7. ^ Wells et al. "1997". 
  8. ^ Levis et al. "1998". 
  9. ^ Cantoni et al. "2001". 
  10. ^ a b Hooper et al. "2001". 
v • d • e
Viral diseases (A80-B34, 042-079)
Viral infections of the CNSPoliomyelitis (Post-polio syndrome) - Subacute sclerosing panencephalitis - Progressive multifocal leukoencephalopathy - Rabies - Encephalitis lethargica - Lymphocytic choriomeningitis - Tick-borne meningoencephalitis - Tropical spastic paraparesis
Arthropod-borne viral fevers and
viral haemorrhagic fevers		Mosquito (Dengue fever - Chikungunya - Rift Valley fever - Yellow fever - O'nyong'nyong - West Nile - Japanese Encephalitis - St. Louis Encephalitis - Murray Valley encephalitis - Ross River) Tick (Crimean-Congo hemorrhagic fever - Omsk hemorrhagic fever - Kyasanur forest disease - Alkurma - Powassan)
Zoonotic viruses (Vector)Menangle - Nipah - BDV Rat (Lassa fever - Venezuelan hemorrhagic fever - Junin - Argentine hemorrhagic fever - Bolivian hemorrhagic fever - Puumala - Andes - Sin Nombre - Haantan) Bat (Australian bat lyssavirus - Ebola - Marburg hemorrhagic fever - Mokola - Duvenhage)
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Viruses and cancersHTLV (induces leukemia) - VSV (oncolytic)
Other viral diseasesCytomegalovirus - Mumps - Bornholm disease
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Andes_virus". A list of authors is available in Wikipedia.
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