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Alpha-Ethyltryptamine



Alpha-Ethyltryptamine
Systematic (IUPAC) name
1-(1H-indol-3-yl)butan-2-amine
Identifiers
CAS number 2235-90-7
ATC code  ?
PubChem  ?
Chemical data
Formula C12H16N2 
Mol. mass 188.27 g/mol
SMILES search in eMolecules, PubChem
Physical data
Melt. point 222–223 °C (432–433 °F)
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status

Schedule I(US)

Routes  ?

alpha-Ethyltryptamine (Etryptamine, α-ethyltryptamine, α-ET, or AET), is a psychoactive drug belonging to the tryptamine family. It was explored as an anti-depressant by Upjohn Chemical Company under the name Monase, but was withdrawn from commercial use after a year due to the unacceptable occurrence of agranulocytosis. It was moved into US Schedule I list of illegal substances in 1993. It is structurally related to α-methyltryptamine but its pharmacological effects are very different. α-ET is not a hallucinogenic drug, its effects resemble more that of the empathogen-entactogens like MDMA (Ecstasy). Alexander Shulgin, in TiHKAL, mentions that this compound has been used to alleviate unpleasant symptoms of opiate withdrawal.

Dosage

75-150 mg is commonly consumed orally for entactogenic effects. α-ET has a stereocenter and S-(+)-α-ET is the more active stereoisomer.

See also

 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Alpha-Ethyltryptamine". A list of authors is available in Wikipedia.
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