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8-Hydroxyquinoline
8-Hydroxyquinoline is an organic compound with the formula C9H6NOH. It is a derivative of the heterocycle quinoline by placement of an OH group on carbon number 8. This colorless compound is widely used commercially, although under a variety of names.[2][3] Additional recommended knowledge
SynthesisIt is usually prepared from quinoline-8-sulfonic acid and from a Skraup synthesis from 2-aminophenol.[4] As a chelating agent8-Hydroxyquinoline is a monoprotic bidentate chelating agent. Related ligands are the Schiff bases derived from salicylaldehyde, such as salicylaldoxime and salen. ApplicationsThe complexes as well as the heterocycle itself exhibit antiseptic, disinfectant, and pesticide properties.[5][6] Its solution in alcohol are used as liquid bandages. It once was of interest as an anti-cancer drug.[7] The roots of the invasive plant Centaurea diffusa release 8-hydroxyquinoline, which has a negative effect on plants that have not co-evolved with it. SafetySee MSDS.[2] References
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This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "8-Hydroxyquinoline". A list of authors is available in Wikipedia. |