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7-Hydroxymitragynine



7-Hydroxymitragynine
IUPAC name 7-Hydroxymitragynine
Properties
Molecular formula C23H30N2O5
Molar mass 414.495 g/mol
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)
Infobox disclaimer and references

7-Hydroxymitragynine, an indole, is an active alkaloid in the plant Mitragyna speciosa, commonly known as Kratom. It has opioid agonistic activity. "The potency, calculated using pD (2) values, was 30- and 17-fold higher than that of mitragynine and morphine, respectively. Antagonism of naloxone on concentration-response curves for 7-hydroxymitragynine confirmed its opioid effect. These results suggest that the opioid effect of M. speciosa is mostly based on the activity of 7-hydroxymitragynine."[1]

See also

  • Mitragynine
  • Mitraphylline
  • Kratom

References

  1. ^ Indole alkaloids of a Thai medicinal herb, Mitragyna speciosa, that has opioid agonistic effect in guinea-pig ileum. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15770543&dopt=Abstract
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "7-Hydroxymitragynine". A list of authors is available in Wikipedia.
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