3-Methoxy-4-hydroxyphenylglycol

3-Methoxy-4-hydroxyphenylglycol

IUPAC name	1-(4-Hydroxy-3-methoxyphenyl)ethane-1,2-diol
Other names	MHPG
Identifiers
CAS number	67423-45-4
PubChem	10805
SMILES	COC1=C(C=CC(=C1)C(CO)O)O
Properties
Molecular formula	C₉H₁₂O₄
Molar mass	184.18918
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

3-Methoxy-4-hydroxyphenylglycol (MHPG) is a metabolite of norepinephrine degradation. In the brain, it is the principal norepinephrine metabolite. It is released into the blood and cerebrospinal fluid,^[1] and a blood sample of it may therefore be an indication of recent sympathetic nervous system activity.

References

^ Increase in cerebrospinal fluid and plasma levels of 3-methoxy-4- hydroxyphenylglycol in acute stroke T Kanda, K Azuma, F Sakai and Y Tazaki. Department of Internal Medicine, School of Medicine, Kitasato University, Sagamihara, Japan.

Category: Metabolism