2C-B-FLY

2C-B-FLY is a psychedelic phenethylamine of the 2C family. It was first synthesized by Aaron P. Monte, and sometimes used as an entheogen.

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Chemistry

2C-B-FLY is 8-bromo-2,3,6,7-benzo-dihydro-difuran-ethylamine. The full name of the chemical is 2-(8-bromo-2,3,6,7-tetrahydrofuro[2,3-f][1]benzofuran-4-yl)ethanamine.

In theory, dihydrodifuran analogues of any of the 2Cx / DOx family of drugs could be made, and would be expected to show similar activity to the parent compound. So in the same way that 2C-B-FLY is the dihydrodifuran analogue of 2C-B, the 8-iodo equivalent 2C-I-FLY would be the dihydrodifuran analogue of 2C-I, and the 8-methyl equivalent 2C-M-FLY would be the dihydrodifuran analogue of 2C-D.

Other related compounds can also be produced, where the alpha carbon of the ethylamine chain is methylated, the amphetamine derivative 3C-B-FLY would be made, this compound being the dihydrodifuran analogue of DOB, and would also be the unsaturated equivalent of Bromo-DragonFLY.

Where only one methoxy group of a 2Cx drug is cyclised into a dihydrofuran ring, the resulting compound is known as a "hemifly", and when an unsaturated furan ring is used the compound is known as a "hemi-dragonfly". A large family of compounds can thus be derived, many of which can be predicted to be active hallucinogens based on the known structure-activity relationships of these drugs, although most of these compounds have not yet been made and tested.

Dosage

Alexander Shulgin lists a dosage of 2C-B-FLY at 10 mg orally.

However, various other information reveals that 2C-B-FLY is active as low as 1 mg^{[citation needed]}.

Effects

2C-B-FLY produces psychedelic effects that last 6-8 hours, or up to 12 hours in larger doses.

Legality

2C-B-FLY is unscheduled and uncontrolled in the United States, but possession and sales of 2C-B-FLY could probably be prosecuted under the Federal Analog Act because of its structural similarities to 2C-B.

Pharmacology

The hallucinogenic effect of 2C-B-FLY is mediated by its partial agonistic activity at the 5-HT_2A serotonin receptor, but 2C-B-FLY also has a high binding affinity for the 5-HT_2B and 5-HT_2C serotonin receptor.

Dangers

The toxicity of 2C-B-FLY is not known.

Popularity

2C-B-FLY is unknown on the black market, though it is available from research chemical vendors that operate on the internet.