Cyano Biotech GmbH

Cyano Biotech GmbH is the global leader in applied R&D on microalgae with a special focus on drug-producing cyanobacteria.

The company's business is based on (1) off-the shelf natural products for research and microalgae water control and (2) contract research for the discovery and development of natural products for the pharmaceutical, chemical, food and cosmetics industries. Besides its own drug discovery program, Cyano Biotech collaborates with international pharmaceutical, agrochemical and life science companies.

• Key products: - Patented new Microcystin payloads, each variant with multi-factorial mode of action + proven efficacy as ADC in picomolar range with favorable safety profile; customized manufacturing at milligram scale - Analytical standards of diverse cyano toxins (e.g. for exact quantification of toxins in water bodies) and bio-reagents of bioactive natural products from cyanobacteria (e.g. for biochemical analysis) - Different formats of natural product libraries for HTS - Contract R&D services: Microcystin libraries for solid + non-solid tumors with variable conjugation and click chemistries + further clickable payload toxins based on Nodularins, Cryptophycins, Largazoles, Apratoxins etc.; production strain development and scale-up for clinical-scale GMP manufacturing

• Core competencies: - Unique strain & compound collection, patent-protected assets and methods, from natural-product-based drug discovery and development to industrial production

• Modern lab and production infrastructure:

- State-of-the-art equipment for natural-product- and ADC-based drug development, cultivation, downstream processing, analytics