Plectonic Biotech GmbH

We use DNA nanotechnology to fight cancer.

The challenge: If cancer cells cannot be recognized by one antigen exclusively, T-cell engaging therapies can lead to on-target off-tumor reactions with severe side-effects.

The Solution: LOGIBODY (LOGIc-gated antiBODY) – a switch for antibody immunotherapies. This ultra-miniaturized nanoswitch made from DNA can specifically recognize cancer cells. The increased specificity allows the immune system to fight cancer in a targeted manner and leads to lower activity on healthy tissue.