Neuron-D GmbH

Our team is a unique combination of scientists and business executives culminating innovative ideas and perfect scientific execution with sustainable financial stability and R&D capacity. We pay special importance to R&D to dynamically match the needs of our customers!

In joint research at the Leibniz Institute for Polymer Research Dresden e.V. (IPF) and the German Center for Neurodegenerative Diseases (DZNE), novel 3D hydrogel cell culture assays based on human neural stem cells have been established by the founders. This system can simulate the endogenous development of the human neurons and mimic neurodegeneration processes in vitro. Our technology was made possible thanks to the innovative bio-inspired materials. In a modularly adaptable platform of hydrogel materials, which is based on sulfated glycosaminoglycans (GAGs) such as heparin that is found in living tissues, and star-shaped branched polyethylene glycol (Star-PEG), which is adaptable in many application-relevant properties in a defined manner. We can generate extensive human neuronal networks by incorporating human neural stem cells into our proprietary matrix (WO2010060485A1 WO2017198258A1).

Compared to the existing neuronal 3D cultures, which can only be modulated to a limited extent and are considerably limited by batch-to-batch variations, our highly reproducible system leads to a faster and more realistic network formation. In our 3D hydrogel system, human neurons acquire a state that is physiologically reminiscent of the neurons in human brains. With our 3D model, we are overcoming several existing hurdles in the field and provide new solutions for drug development efforts!

- We offer you something different! - We offer you an innovative science! - We offer you the world-class scientific guidance!